8 racial adjustment of predicted value most studies for normal values in us looked at caucasian populations of normals not apppp p g propriate for other ethnic groups if used in african american population more likely to seem abnormal 12 higher controversial.
Abnormal rv tlc ratio.
Adjustment of predicted value downward reduces the sensitivity of the test for detecting abnormality.
An abnormal rv tlc ratio has been documented in adults with severe persistent asthma.
A significant bronchodilator response was observed in 32 of the patients.
Then taking the ratio of observed and predicted intro duces an age related bias an undesirable feature.
Furthermore there was no correlation between fev1 reversibility and rv reversibility r 0 1 p 0 3 conclusions.
While fev1 improvement with bronchodilator may be a function of large airway reversibility lack of significant rv reversibility may indicate small airway closure that is non reversible.
A positive correlation was observed between rv to age r 0 4 and height r 0 3.
Agreement and bias normal abnormal kappa bias p value plethysmography actual 40 40 79 5 yes 0 0006.
Abnormal rv tlc ratio was a superior criterion for diagnosing obstruction in asthma.
Aalternative ccriteria oof nnormality.